NOX1 antibody (C-Term)

Catalog No. ABIN372303

This anti-NOX1 antibody is a Rabbit Polyclonal antibody detecting NOX1 in WB, IHC (p) and EIA. Suitable for Human.

Quick Overview for NOX1 antibody (C-Term) (ABIN372303)

Target: NOX1 (NADPH Oxidase 1 (NOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-NOX1 Antibody

Binding Specificity: C-Term

Specificity: This antibody recognizes NADPH Oxidase 1 (NOX1).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to C-terminal residues of Human NOX1.

Isotype: IgG

Application Details

Application Notes: ELISA: 1 μg/mL. Western Blot: 1 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for NOX1

Target: NOX1 (NADPH Oxidase 1 (NOX1))

Alternative Name: NOX-1

Background: The NOX family NADPH protein oxidases are involved in transfer of electrons accross membranes to generate reactive oxygen species. There are 7 family members - NOX1-5, DUOX1 and DUOX2. Expression of NOX1 is highest in colon tissue, it is also found in vascular tissue and can also been induced by a variety of factors including PDGF. It requires interaction with NOXO1 and NOXA1 for superoxide generation.Synonyms: Mitogenic oxidase 1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NADPH oxidase 1, NOH1

Molecular Weight: 65 kDa.

Gene ID: 27035

NCBI Accession: NP_008983

UniProt: Q9Y5S8

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport